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Rating 4.7
500+ reviews

Weight loss built for your health

We create personalized weight loss plans to help you feel your best — powered by PermeAct™ Delivery Tech for better absorption and more consistent results.

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our products

Modern solutions for weight loss & healthy aging

how it works

It’s much easier than you think

Injection-Free

Clinically proven next-gen delivery technology

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Steve Kushner
Founder, Chief Scientist
and Formulator

PermeAct™ Delivery Technology

It is a proprietary delivery system designed to significantly enhance the uptake and bioavailability of active ingredients.

Unlike conventional methods, it works effectively regardless of particle size, maximizing ingredient performance. The technology can be adjusted to work locally or throughout the body.


PermeAct™ has been tested in lab settings, animal studies, and human clinical trials, showing it can help deliver compounds that normally struggle to penetrate tissue, leading to both targeted and whole-body benefits.

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Featured in leading scientific publications, including:

Journal of the Royal Society of Chemistry • FASEB Journal • American Journal of Clinical Nutrition • Journal of Addiction Research & Therapy • American Journal of Biomedical Science & Research

How it works

1

Delivery system activates

The delivery system activates upon use, preparing ingredients for more efficient absorption.

2

Cellular pathways open

The system creates a short-lived bioelectric response that opens cellular pathways for improved uptake.

3

Active Ingredients absorb

This enables ingredients to reach their target more efficiently, supporting stronger and more consistent results.

Science-backed answers for peace of mind

What makes PermeAct™ different from other delivery technologies?

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How does PermeAct™ actually work?

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Is PermeAct™ scientifically tested?

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Why Choose Us

Healthcare that
feels human, not clinical

tREATMENT

Clinically proven treatments, safely prescribed

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Care

Access to our team
of licensed clinicians

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Support

Care on your schedule,
no visits required

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Benefits

Make today life changing

Improve your body health
Losing even 10% of body weight may support heart health, boost energy, and improve sleep quality.
Rebuild your confidence
Reaching a healthier weight can meaningfully boost self-esteem and reshape how you see yourself.
Strengthen your mental well-being
Weight loss can reduce stress, stabilize mood, and support clearer emotional balance.

Alyve members lose

11-20%
body weight
in 12 months
Based on studies of the highest dose in non-diabetics with obesity, or with overweight plus a weight-related condition, with diet and exercise.
How much weight can you lose by next spring?
Your current weight:
220
With Alyve you could lose:
33 lbs
Results You Can See

Alyve treatments are transforming lives

Why choose us

Brand new weight loss & longevity treatments

Others
Online assessment
Fast, private and available 24/7
In-person visits
Long waits, travel time and limited privacy
VS
Targeted treatments
Scientifically proven & tailored to your individual needs
One solution for all
Generic treatments that ignore individual differences
VS
Injection-free alternatives
Enhanced absorption and more consistent results
Traditional treatments
Injection fatigue or inconsistent oral performance
VS
Weight loss experts
Trusted by over 20k+ patients experiencing weight loss
Limited experience
Not specialised in treating weight gain
VS
Unlimited free support
Continued monitoring for your peace-of-mind
No support
Not guidance post prescription
VS
FAQ

Have more questions?

What makes Alyveᴿˣ different from all of the other companies out there?

Alyveᴿˣ has been involved in the weight loss and peptide industry for years and are the creators of the PermeAct™ Delivery Technology. They identified a major gap in the market — many patients who could benefit from life-changing medications were held back by a fear of needles, leaving them without access to effective treatment. Alyveᴿˣ solved this problem by developing sublingual and transdermal delivery methods, making these medications accessible to everyone.

Does Alyveᴿˣ requireinsurance?

No, you don’t need insurance to make treatment accessible! Our care model is designed to make access straightforward and affordable without requiring coverage.

What medications do Alyveᴿˣ providers prescribe?

Our network of partner physicians may prescribe FDA-approved and compounded medications. Other offerings may include peptide therapies and medications that support metabolism, recovery, or performance; based on clinical suitability and your health goals.
Note: Compounded medications are prepared based on specific patient needs and are not reviewed or approved by the FDA for safety or effectiveness. Prescription required. Results may vary.

What makes PermeAct™ different from other delivery technologies?

PermeAct™ delivery technology is different from other delivery technologies in several ways.
It has been clinically researched and validated in several different formats and also been featured in various clinical studies in finished formulations that have resulted in publications in scientific journals.
The delivery technology is capable of use in both topical and oral products and consist of all GRAS ingredients making it safe for use in any format.
To date, we have not found any compound of any particle size that we cannot deliver through physiological tissue to create a positive effect both locally and systemically.
The PermeAct™ technology does not affect the compound or carrier vehicle. Instead, it reacts with surface tissue that allows for both sublingual and transdermal permeation.

How does PermeAct™ actually work?

PermeAct™ Delivery Tech also know as ALM Delivery Technology is a unique and proprietary delivery technology shown to enhance active ingredient uptake and bioavailability, regardless of particle size.
Produced using a highly specific and proprietary process, it not only helps amplify the absorption and bio-availability of ingredients, but also provides a direct benefit to cellular physiology.
Effects can be made more or less assertive as desired (to keep active compounds local or create a more systemic effect).

The self-contained delivery system creates a phenomenon akin to electroporation, in which electrostatic repulsion creates short-lived electric voltage pulses. This opens ionic channels on physiologic tissue allowing delivery of constituents, either topically of orally.

Is PermeAct™ scientifically tested?

PermeAct™ Delivery Tech has been evaluated in human skin tissue cultures, animal testing (non-cruel), and human studies including double-blind placebo-controlled studies. The technology has been demonstrated to be capable of creating physiological responses with compounds that would normally be unable to penetrate tissue membranes, creating both profound local and/or definitive systemic benefits.

A number of articles have appeared in peer reviewed journals featuring proprietary formulations combined with differing iterations of the PermeAct™ Delivery Tech. Some of the better-known publications include The Journal of The Royal Society of Chemistry, The Journal of FASEB (Federation of American Societies of Experimental Biology), The American Journal of Clinical Nutrition, The Journal of Addiction Research & Therapy, and The American Journal of Biomedical Science & Research.